Rent for a home office is deductible based on the percentage of your home used exclusively for business. To calculate this, measure the square footage of your office space and divide it by the total square footage of your home to determine the percentage. For example, if your office takes up 10% of your home, you can deduct 10% of the total rent payments. The space must be used exclusively and regularly for business activities, and not for personal use. It's essential to maintain proper documentation, including a floor plan, lease agreements, and measurements to substantiate the deduction. This helps ensure that your home office meets IRS criteria and that you’re complying with all tax rules, maximizing the benefits of this deduction and lowering your taxable income.